Anti-Mouse CD45.2 Antibody, Clone 104

Mouse monoclonal IgG2a antibody against mouse CD45.2
Catalog #
60118_C
Mouse monoclonal IgG2a antibody against mouse CD45.2
From: 58 EUR

Overview

The 104 monoclonal antibody reacts with mouse alloantigen CD45.2 (Ly5.2) expressed by all hematopoietic cells except mature erythrocytes and platelets in mouse strains A, AKR, BALB/c, CBA/Ca, CBA/J, C3H/He, C57BL, C57BR, C57L, C58, DBA/1, DBA/2, NZB, SWR, and 129. Clone 104 does not react with leukocytes that express CD45.1 alloantigen. CD45.2 is an allelic form of CD45 (Leukocyte common antigen), a 180 - 240 kD type I transmembrane glycoprotein. CD45 is a member of the protein tyrosine phosphatase (PTP) family and functions in a number of immunoregulatory processes, including cell activation, growth, lymphocyte development, differentiation, and oncogenic transformation. The isoforms of CD45 correlate to specific cell types, as well specific activation and maturation states of immune cells. The 104 monoclonal antibody has been used extensively in adoptive cell transfer and bone marrow transplantation studies in mice, allowing for the differentiation of CD45.2- and CD45.1- expressing cells.
Subtype
Primary Antibodies
Target Antigen
CD45.2
Reactive Species
Mouse
Conjugation
Biotin
Host Species
Mouse
Cell Type
Granulocytes and Subsets, Hematopoietic Stem and Progenitor Cells, Lymphocytes, Myeloid Cells
Species
Mouse
Application
Flow Cytometry
Area of Interest
Immunology

Scientific Resources

Product Documentation

Document Type Product Name Catalog # Lot # Language
Document Type
Product Information Sheet
Product Name
Anti-Mouse CD45.2 Antibody, Clone 104, Biotin
Catalog #
60118BT, 60118BT.1
Lot #
All
Language
English
Document Type
Safety Data Sheet
Product Name
Anti-Mouse CD45.2 Antibody, Clone 104, Biotin
Catalog #
60118BT, 60118BT.1
Lot #
All
Language
English

Educational Materials (2)

Brochure
Reliable Antibodies for Your Research
Wallchart
Human Immune Cytokines

Product Applications

This product is designed for use in the following research area(s) as part of the highlighted workflow stage(s). Explore these workflows to learn more about the other products we offer to support each research area.

Data and Publications

Data

Data for Biotin-Conjugated

Figure 1. Data for Biotin-Conjugated

Flow cytometry analysis of C57BL/6 mouse splenocytes labeled with Anti-Mouse CD45.2 Antibody, Clone 104, Biotin followed by streptavidin (SAV) APC (filled histogram) or Mouse IgG2a, kappa Isotype Control Antibody, Clone MOPC-173, Biotin (Catalog #60071BT) followed by SAV APC (solid line histogram).

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