NBQX (Sodium Salt)

AMPA receptor antagonist

NBQX (Sodium Salt)

AMPA receptor antagonist

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AMPA receptor antagonist
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Overview

NBQX is a neuroprotective agent and a potent and competitive AMPA receptor antagonist (IC50 = 0.15 µM; Sheardown et al.). AMPA receptors are cation channels and ionotropic glutamate transmembrane receptors that play an important role in the function of the human nervous system, such as in learning and memory (Gouaux). AMPA receptors are therapeutic targets for neurological diseases (Chang et al.).

DISEASE MODELING
· Reduces cerebral ischemic necrosis in the hippocampus (Gaspary et al.).
Cell Type
Neurons
Area of Interest
Disease Modeling, Neuroscience
CAS Number
479347-86-9
Chemical Formula
C12H6N4O6S • 2Na
Molecular Weight
380.2 g/mol
Purity
≥ 98%

Protocols and Documentation

Find supporting information and directions for use in the Product Information Sheet or explore additional protocols below.

Document Type
Product Name
Catalog #
Lot #
Language
Catalog #
100-0891
Lot #
All
Language
English
Document Type
Safety Data Sheet
Catalog #
100-0891
Lot #
All
Language
English