ME0328

PARP-3 inhibitor

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PARP-3 inhibitor
From: 42 USD

Overview

ME0328 is a cell-permeable and selective inhibitor of poly(ADP-ribose) polymerase 3 (PARP-3; IC₅₀ = 0.89 µM; Lindgren et al.). PARP-3 is required for stabilization of the mitotic spindle and crucial for mitotic progression (Sharif-Askari et al.).

CANCER RESEARCH
· Enhances vinorelbine-induced microtubule destabilization, leading to cell cycle arrest and apoptosis in breast cancer cells (Sharif-Askari et al.).
CAS Number:
1445251-22-8
Chemical Formula:
C₁₉H₁₉NO
Molecular Weight:
321.4 g/mol
Purity:
≥ 98%
Target:
PARP3

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PRODUCTS ARE FOR RESEARCH USE ONLY AND NOT INTENDED FOR HUMAN OR ANIMAL DIAGNOSTIC OR THERAPEUTIC USES UNLESS OTHERWISE STATED. FOR ADDITIONAL INFORMATION ON QUALITY AT STEMCELL, REFER TO WWW.STEMCELL.COM/COMPLIANCE.