L755507

Activates β-3 adrenergic receptors
Catalog #
73992_C
Activates β-3 adrenergic receptors
From: 118 USD

Overview

L755507 is a potent and selective β-3 adrenergic receptor agonist that demonstrates > 440-fold selectivity over β-1 and β-2 binding (EC50 = 0.43, 580, and > 10,000 nM for activation of cloned human β-3-, β-2-, and β-1-adrenoreceptors, respectively; Parmee et al.).

DIFFERENTIATION
· Stimulates lipolysis in human white adipose tissue (Fisher et al.).

GENE EDITING
· Improves the efficiency of homology-directed repair in human induced-pluripotent stem cells following CRISPR editing (Yu et al.).

METABOLISM
· Increases metabolism in rhesus monkeys (Fisher et al.).
Alternative Names
Not applicable
Cell Type
Adipocytes, Pluripotent Stem Cells
Species
Human, Mouse, Rat, Non-Human Primate, Other
Application
Differentiation, Reprogramming
Area of Interest
Stem Cell Biology
CAS Number
159182-43-1
Chemical Formula
C₃₀H₄₀N₄O₆S
Molecular Weight
584.7 g/mol
Purity
≥ 98%

Related Products

Scientific Resources

Product Documentation

Document Type Product Name Catalog # Lot # Language
Document Type
Product Information Sheet 1
Product Name
L755507
Catalog #
73992, 73994
Lot #
All
Language
English
Document Type
Product Information Sheet 2
Product Name
L755507
Catalog #
73992, 73994
Lot #
All
Language
English
Document Type
Safety Data Sheet
Product Name
L755507
Catalog #
73992, 73994
Lot #
All
Language
English

Educational Materials(5)

Brochure
Small Molecules for Cancer Research
Brochure
Cytokines, Chemokines and Growth Factors
Brochure
Small Molecules for Stem Cell Research
Wallchart
Small Molecules, Big Impact in Pluripotent Stem Cell Research
Wallchart
Small Molecules, Big Impact in Cancer Research

Product Applications

This product is designed for use in the following research area(s) as part of the highlighted workflow stage(s). Explore these workflows to learn more about the other products we offer to support each research area.

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