L755507

Activates β-3 adrenergic receptors

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Activates β-3 adrenergic receptors
From: 111 USD

Overview

L755507 is a potent and selective β-3 adrenergic receptor agonist that demonstrates > 440-fold selectivity over β-1 and β-2 binding (EC50 = 0.43, 580, and > 10,000 nM for activation of cloned human β-3-, β-2-, and β-1-adrenoreceptors, respectively; Parmee et al.).

DIFFERENTIATION
· Stimulates lipolysis in human white adipose tissue (Fisher et al.).

GENE EDITING
· Improves the efficiency of homology-directed repair in human induced-pluripotent stem cells following CRISPR editing (Yu et al.).

METABOLISM
· Increases metabolism in rhesus monkeys (Fisher et al.).
Alternative Names:
Not applicable
CAS Number:
159182-43-1
Chemical Formula:
C₃₀H₄₀N₄O₆S
Molecular Weight:
584.7 g/mol
Purity:
≥ 98%

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Product Applications

This product is designed for use in the following research area(s) as part of the highlighted workflow stage(s). Explore these workflows to learn more about the other products we offer to support each research area.

STEMCELL TECHNOLOGIES INC.’S QUALITY MANAGEMENT SYSTEM IS CERTIFIED TO ISO 13485. PRODUCTS ARE FOR RESEARCH USE ONLY AND NOT INTENDED FOR HUMAN OR ANIMAL DIAGNOSTIC OR THERAPEUTIC USES UNLESS OTHERWISE STATED.