Human Amyloid-β (1-42) Peptide (Trifluoroacetate Salt)

Neurotoxic peptide fragment
Human Amyloid-β (1-42) Peptide (Trifluoroacetate Salt)

Neurotoxic peptide fragment

0.5 mg
Catalog # 100-0899
555 USD

Overview

Human Amyloid-β (1-42) Peptide is a neurotoxic peptide fragment that can oligomerize to form amyloid plaques, thus contributing to the onset of Alzheimer's disease (Paradis et al.; Teplow; Wolfe). These neurotoxic peptide fragments also modulate the expression of Bcl-2 and Bax in human neurons (Paradis et al.).

NOTE: Human Amyloid-β (1-42) Peptide oligomers and fibrils are considered neurotoxic. Please contact your workplace safety committee for guidance before planning any work using Human Amyloid-β (1-42) Peptide.

DISEASE MODELING
· Induces neuronal death in human neurons in vitro and in vivo (Paradis et al.).
· Increases production of TNF-α in rat astrocytes (Hughes et al.).
Alternative Names
Aβ (1-42); Aβ42
Cell Type
Neurons
Area of Interest
Disease Modeling, Neuroscience
Purity
≥ 95 %

Scientific Resources

Product Documentation

Document Type Product Name Catalog # Lot # Language
Document Type
Product Information Sheet
Product Name
Human Amyloid-β (1-42) Peptide (Trifluoroacetate Salt)
Catalog #
100-0899
Lot #
All
Language
English
Document Type
Safety Data Sheet
Product Name
Human Amyloid-β (1-42) Peptide (Trifluoroacetate Salt)
Catalog #
100-0899
Lot #
All
Language
English

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