STEMprep™ Tissue Dissociator | Automated Tissue Dissociation for High-Quality Single-Cell Suspensions
STEMprep™ Tissue Dissociator
Automated Tissue Dissociation for High-Quality Single-Cell Suspensions
Research and development in various fields, including cancer and immunology, rely on single-cell suspensions for use in applications such as flow cytometry and single-cell sequencing. Effective tissue dissociation methods are needed to generate single-cell suspensions with high viability. However, conventional manual dissociation methods can be labor-intensive, inconsistent, and prone to variability, all of which can negatively affect reproducibility and data accuracy.
To address these challenges, we developed the STEMprep™ Tissue Dissociation System—an automated solution that standardizes and streamlines the dissociation process. With built-in temperature control, modular scalability, and an intuitive interface, STEMprep™ ensures efficient, reproducible, and high-yield single-cell suspensions from a wide range of solid tissues while preserving epitope integrity and cell functionality.
Why Use STEMprep™?
- Standardize tissue dissociation with automation for consistent, reproducible results.
- Obtain high numbers of viable single cells with preserved functionality for downstream applications.
- Ensure optimal sample processing for various sample types and applications with built-in temperature control from 4 to 37°C.
- Choose from a 4-sample, 8-sample, or 12-sample system—scaling seamlessly to meet increasing throughput needs while maintaining efficiency.
- Use validated STEMCELL protocols or create your own to adapt STEMprep™ to different tissue types and experimental needs.
Interactive Product Tour
Explore the STEMprep™ Tissue Dissociator in this interactive tour. Click on its key parts and discover how each helps make tissue processing efficient and produces high-quality single-cell preparations.
STEMprep™ Products
STEMprep™ Tissue Dissociator
Description:
Advantages:
- Standardize tissue dissociation for consistent, reproducible results.
- Achieve high numbers of viable, functional single cells.
- Maintain optimal processing with temperature control from 4 to 37°C.
- Start with a 4-, 8-, or 12-sample system and scale as needed.
- Use STEMCELL protocols or create your own for various tissue types and needs.
Size:
8-Sample System
12-Sample System
Note: If you need to go beyond the 12-sample system, you can purchase an additional Expansion Unit to increase sample capacity by 4.
STEMprep™ Tissue Dissociation Kits
Description:
Advantages:
- Achieve reproducible tissue dissociation when used with the STEMprep™ Tissue Dissociator
- Ensure gentle yet effective tissue processing by combining enzymatic digestion and mechanical dissociation
- Generate reliable single-cell suspensions
- Obtain high numbers of viable cells
Size:
STEMprep™ Sample Tubes
Description:
Advantages:
- Enable reproducible tissue dissociation with the STEMprep™ Tissue Dissociator
- Support a wide range of input sizes (20 - 4000 mg) and volumes (1 - 10 mL)
- Minimize user variability for consistent downstream results
- Protect sample integrity with single-use format
Size:
Seamless Integration into Your Workflow
STEMprep™ integrates with STEMCELL Technologies’ tissue processing and cell isolation solutions, enabling an end-to-end workflow. Resultant cell suspensions can be used with EasySep™ for column-free cell isolation; ImmunoCult™ immune cell culture media, activators, and supplements; or other STEMCELL reagents to maximize cell purity and recovery.
Figure 1. STEMprep™ Tissue Dissociation Workflow
The STEMprep™ Tissue Dissociator enables efficient processing of various tissue types, including mouse brain, liver, lung, spleen, and tumors. In this workflow, a tissue is placed into the STEMprep™ sample tube and processed using the STEMprep™ Tissue Dissociator. Depending on the selected protocol—dissociation or homogenization—the resulting sample will either be a single-cell suspension or nucleic acids. The processed sample can then be used for various downstream applications, such as cell isolation, activation, culture, and analysis.
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