Benztropine (Mesylate)

Acetylcholine muscarinic m1 receptor antagonist

Benztropine (Mesylate)

Acetylcholine muscarinic m1 receptor antagonist

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Acetylcholine muscarinic m1 receptor antagonist
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Overview

Benztropine is an acetylcholine muscarinic m1 receptor antagonist (Ki = 0.59 nM; Sogawa et al.) and a dopamine reuptake inhibitor (Deshmukh et al.). The pharmacological properties of benztropine can help patients manage the symptoms (e.g. tremors) of Parkinson's disease (Deshmukh et al.). Benztropine can also inhibit tumor growth, reduce the number of circulating tumor cells, and suppress metastasis of allograft tumors (Sogawa et al.).

DIFFERENTIATION
· Induces oligodendrocyte precursor cell differentiation in vitro (Deshmukh et al.).
CANCER RESEARCH
· Reduces size and number of mammospheres in human breast cancer cells (Cui et al.).
Alternative Names
NSC 169913
Cell Type
Cancer Cells and Cell Lines
Area of Interest
Cancer, Disease Modeling, Neuroscience
CAS Number
132-17-2
Chemical Formula
C21H25NO • CH3SO3H
Molecular Weight
403.5 g/mol
Purity
≥ 98%

Protocols and Documentation

Find supporting information and directions for use in the Product Information Sheet or explore additional protocols below.

Document Type
Product Name
Catalog #
Lot #
Language
Catalog #
100-0889
Lot #
All
Language
English
Document Type
Safety Data Sheet
Catalog #
100-0889
Lot #
All
Language
English