Anti-Human HLA-DR Antibody, Clone LN3

Mouse monoclonal IgG2b antibody against human, rhesus HLA-DR
Catalog #
60164_C
Mouse monoclonal IgG2b antibody against human, rhesus HLA-DR
From: 131 USD

Overview

The LN3 antibody reacts with the HLA-DR antigen, a major histocompatibility complex (MHC) class II receptor encoded within the human leukocyte antigen (HLA) complex on chromosome 6. HLA-DR is a heterodimeric transmembrane glycoprotein comprising non-covalently associated α (36 kDa) and β (27 kDa) subunits. MHC class II plays a central role in the presentation of antigen-derived peptides to CD4+ T cells, along with CD3/TCR and CD4. HLA-DR is primarily expressed on the surface of antigen-presenting cells, including B cells, dendritic cells, monocytes, macrophages, thymic epithelial cells, and activated T and natural (NK) cells. The LN3 antibody binds to an extracellular epitope that reportedly resides within the HLA-BR1 subunit of HLA-DR.
Subtype
Primary Antibodies
Target Antigen
HLA-DR
Alternative Names
HLA class II histocompatibility antigen, HLA-DR alpha, HLA-DRA, HLA DRA1, HLA DR1B, HLA DR3B, HLA DRB1, HLA DRB3, HLA DRB4, HLA DRB5, HLADR4B, HLADRA1, HLADRB, Major histocompatibility class II, MHC II, MHC class II, MHC class II antigen DRA, MLRW
Reactive Species
Rhesus, Human
Conjugation
Alexa Fluor 488, FITC, PE, Unconjugated
Host Species
Mouse
Cell Type
B Cells, Dendritic Cells, Macrophages, Monocytes, Other, T Cells
Application
Flow Cytometry, Functional Assay, Immunohistochemistry
Area of Interest
HLA, Immunology, Infectious Diseases, Transplantation Research
Clone
LN3
Gene ID
3123
Isotype
IgG2b, kappa

Scientific Resources

Product Documentation

Document Type Product Name Catalog # Lot # Language
Document Type
Product Information Sheet
Product Name
Anti-Human HLA-DR Antibody, Clone LN3
Catalog #
60164
Lot #
All
Language
English
Document Type
Product Information Sheet
Product Name
Anti-Human HLA-DR Antibody, Clone LN3, Alexa Fluor® 488
Catalog #
60164AD
Lot #
All
Language
English
Document Type
Product Information Sheet
Product Name
Anti-Human HLA-DR Antibody, Clone LN3, FITC
Catalog #
60164FI, 60164FI.1
Lot #
All
Language
English
Document Type
Product Information Sheet
Product Name
Anti-Human HLA-DR Antibody, Clone LN3, PE
Catalog #
60164PE, 60164PE.1
Lot #
All
Language
English
Document Type
Safety Data Sheet
Product Name
Anti-Human HLA-DR Antibody, Clone LN3
Catalog #
60164
Lot #
All
Language
English
Document Type
Safety Data Sheet
Product Name
Anti-Human HLA-DR Antibody, Clone LN3, Alexa Fluor® 488
Catalog #
60164AD
Lot #
All
Language
English
Document Type
Safety Data Sheet
Product Name
Anti-Human HLA-DR Antibody, Clone LN3, FITC
Catalog #
60164FI, 60164FI.1
Lot #
All
Language
English
Document Type
Safety Data Sheet
Product Name
Anti-Human HLA-DR Antibody, Clone LN3, PE
Catalog #
60164PE, 60164PE.1
Lot #
All
Language
English

Educational Materials (3)

Brochure
Reliable Antibodies for Your Research
Brochure
HLA Antibodies for Purity Assessment
Wallchart
Human Immune Cytokines

Product Applications

This product is designed for use in the following research area(s) as part of the highlighted workflow stage(s). Explore these workflows to learn more about the other products we offer to support each research area.

Research Area
Workflow Stages

Data and Publications

Data

Flow cytometry analysis of human peripheral blood mononuclear cells (PBMCs) labeled with Anti-Human HLA-DR Antibody, Clone LN3, followed by an anti-mouse IgG2b antibody, PE (filled histogram), or Mouse IgG2b, kappa Isotype Control Antibody, Clone MPC-11 (Catalog #60072), followed by an antimouse IgG2b antibody, PE (solid line histogram).

Flow cytometry analysis of human peripheral blood mononuclear cells (PBMCs) labeled with Anti-Human HLA-DR Antibody, Clone LN3, FITC (filled histogram), or Mouse IgG2b, kappa Isotype Control Antibody, Clone MPC-11, FITC (Catalog #60072FI; solid line histogram).

Flow cytometry analysis of human peripheral blood mononuclear cells (PBMCs) labeled with Anti-Human HLA-DR Antibody, Clone LN3, PE (filled histogram), or Mouse IgG2b, kappa Isotype Control Antibody, Clone MPC-11, PE (Catalog #60072PE; solid line histogram).

Flow cytometry analysis of human peripheral blood mononuclear cells (PBMCs) labeled with Anti-Human HLA-DR Antibody, Clone LN3, Alexa Fluor® 488 (filled histogram), or Mouse IgG2b, kappa Isotype Control Antibody, Clone MPC-11, Alexa Fluor® 488 (Catalog #60072AD; solid line histogram).

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