Diseased Human Peripheral Blood Products, Diabetes,Type I

Diseased primary human cells, fresh or frozen

Diseased Human Peripheral Blood Products, Diabetes,Type I

Diseased primary human cells, fresh or frozen

From: 788 USD
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Diseased primary human cells, fresh or frozen
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Product Advantages


  • Get large numbers of diseased cells at a given time point from a single-donor

  • Obtain PBMCs and a range of immune cell subsets from a single leukopak

  • Allow for flexibility in your workflow by being able to freeze cells for future experiments


Overview

Start your research confidently with a reliable supply of ethically sourced, peripheral blood (PB) products from donors diagnosed with celiac disease (CD). CD is an autoimmune condition characterized by a specific serological and histological profile triggered by gluten ingestion in genetically predisposed individuals. Cells from donors with celiac disease can be used as an epithelial cell model to demonstrate the pathological effects induced by gluten exposure. Product options include half or full fresh leukopaks and frozen mononuclear cells (MNCs or PBMCs). We help you get the cells you need with personalized service and flexible delivery times.

Leukopaks are an enriched leukapheresis product consisting of a large number of single-donor MNCs. Each full-sized leukopak is produced from ~2 - 3x blood volumes using the Spectra Optia® Apheresis System, with acid-citrate-dextrose solution A (ACDA) as the anticoagulant. Primary human MNCs are isolated from peripheral blood, leukapheresis, or whole blood samples using density gradient separation or red blood cell lysis and cryopreserved in animal component-free CryoStor®CS10 medium (Catalog #07930). All PB products are obtained from donors diagnosed with CD using Institutional Review Board (IRB)-approved consent forms and protocols. Additional documentation and high-resolution HLA typing (Class I and Class II alleles) may be available upon request. Donor specifications (e.g. BMI category, age, ethnicity, etc.) can be requested in the comment box above, after selecting from the product options. Donors are screened for HIV-1, HIV-2, hepatitis B, and hepatitis C.

Certain products are only available in select territories. Please contact your local sales representative or Product & Scientific Support at techsupport@stemcell.com for further information.

Browse our Frequently Asked Questions (FAQs) on Primary Cells.
Contains
•   CryoStor® CS10
Subtype
Fresh, Frozen
Cell Type
Leukopaks, Mononuclear Cells, T Cells, Whole
Species
Human
Cell and Tissue Source
Peripheral Blood
Application
Activation, Cell Culture, Cell Isolation, Cryopreservation, Expansion, Genome Editing
Area of Interest
Disease Modeling, Drug Discovery and Toxicity Testing

Protocols and Documentation

Find supporting information and directions for use in the Product Information Sheet or explore additional protocols below.

Document Type
Product Name
Catalog #
Lot #
Language
Catalog #
200-0751
Lot #
All
Language
English
Catalog #
200-0760
Lot #
All
Language
English
Catalog #
70061
Lot #
All
Language
English

Applications

This product is designed for use in the following research area(s) as part of the highlighted workflow stage(s). Explore these workflows to learn more about the other products we offer to support each research area.