SU5402

MEK/ERK pathway inhibitor; Inhibits VEGFR2, FGFR1, and PDGFRB

SU5402

MEK/ERK pathway inhibitor; Inhibits VEGFR2, FGFR1, and PDGFRB

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MEK/ERK pathway inhibitor; Inhibits VEGFR2, FGFR1, and PDGFRB
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Overview

SU5402 is a potent and selective inhibitor of vascular endothelial growth factor receptor 2 (VEGFR-2), fibroblast growth factor receptor 1 (FGFR-1), and platelet-derived growth factor receptor beta (PDGFRB) with IC50 = 0.02, 0.03, and 0.51 µM, respectively (Sun et al.).
Cell Type
Cancer Cells and Cell Lines, Hybridomas, Pluripotent Stem Cells
Species
Human, Mouse, Non-Human Primate, Other, Rat
Application
Maintenance
Area of Interest
Antibody Development, Cancer, Disease Modeling, Hybridoma Generation, Immunology, Stem Cell Biology
CAS Number
215543-92-3
Chemical Formula
C₁₇H₁₆N₂O₃
Purity
≥ 95%
Pathway
MEK/ERK
Target
FGFR, PDGFR

Protocols and Documentation

Find supporting information and directions for use in the Product Information Sheet or explore additional protocols below.

Document Type
Product Name
Catalog #
Lot #
Language
Product Name
SU5402
Catalog #
73912, 73914
Lot #
For orders placed 2019-11-26 or earlier
Language
English
Product Name
SU5402
Catalog #
73912, 73914
Lot #
For orders placed 2019-11-27 or later
Language
English
Document Type
Safety Data Sheet
Product Name
SU5402
Catalog #
73912, 73914
Lot #
All
Language
English

Applications

This product is designed for use in the following research area(s) as part of the highlighted workflow stage(s). Explore these workflows to learn more about the other products we offer to support each research area.