In Vitro Immunology Tools for NAMs

In drug discovery, the immune system is both a therapeutic target and a frequent source of safety risk. From immuno-oncology and cell therapy development, to autoimmunity and inflammatory disease research, human immune cell models allow you to assess cytotoxicity, cytokine release, and immune activation, suppression, and modulation. Human immune cell models are critical for assessing immunotoxicity in biologic and small-molecule programs, including risks such as cytokine release syndrome or unintended immunosuppression. By enabling mechanistic immune profiling and scalable functional testing in physiologically relevant systems, human in vitro immune platforms support your development and implementation of new approach methodologies (NAMs).

Immune cell models can also strengthen your translational research by supporting disease modeling, target validation, and biomarker discovery. Quantitative assessment of cytokine production, proliferation, phenotype, and functional activity enables identification of predictive immune response markers and supports more informed candidate selection. Incorporating human immune systems into your development workflows improves risk assessment and helps guide safer, more effective therapeutic strategies.

Explore in vitro immune system tools for your NAM development.