Induced pluripotent stem (iPS) cells are a type of pluripotent stem cell (PSC) that can be obtained by reprogramming somatic cells through artificial expression of key transcription factors under specific culture conditions.1-2 See More Variables that affect reprogramming include the delivery method, culture conditions and starting cell type. The choice of starting cell type is influenced by factors such as availability of donor tissue, invasiveness of sample collection procedures, genomic integrity, epigenetic memory and reprogramming efficiency. For efficient reprogramming, use our non-viral and non-integrating vector system, , and small molecules. For blood-derived cells, we offer integrated kits to enrich, isolate, expand and reprogram erythroid progenitor or CD34+ progenitor cells. For help with your hPSC workflow decision making, use our to find the right reagents for you.
- Brochure ReproRNA™-OKSGM Non-Integrating Reprogramming Vector
- Technical Bulletin TeSR™-E7™ Episomal Protocol
- Tech Tip Tips for Reprogramming Somatic Cells using TeSR™-E7™
- Wallchart Pluripotent Stem Cell Biology
- Brochure An Integrated Workflow for Reprogramming Blood Cells
- Takahashi K, et al. Cell 131(5): 861–72, 2007
- Yu J, et al. Science 318(5858): 1917–20, 2007