For researchers studying neurological development and disease, cryopreserved human pluripotent stem cell (hPSC)-derived neural cells can be a valuable tool. See MoreUsing cryopreserved neural progenitor cells (NPCs) or lineage-restricted neuronal and glial precursors enables rapid and reproducible implementation of hPSC neural models, bypassing the need for time-consuming and variability-prone hPSC maintenance and neural induction steps. Furthermore, a reliable source of large quantities of cells with a reproducible phenotype is critical for high-throughput screening applications, such as drug screening and toxicology testing.
Highly pure cryopreserved hPSC-derived NPCs are available from various cell lines. These NPCs express the neural progenitor markers SOX1 and Nestin. The cells can be expanded with Neural Progenitor Medium 2 and passaged for over 10 passages without loss of differentiation capacity.
Cryopreserved hPSC-derived mixed neurons, dopaminergic neurons or astrocytes can be matured from their precursor states using the corresponding STEMdiff™ Maturation Kit.
Primary and Cultured Cells (46)
Cryopreserved human PSC-derived neural progenitor cells for expansion and differentiation
Cryopreserved human PSC-derived neuronal precursor cells for maturation into forebrain-type neurons
Cryopreserved human PSC-derived dopaminergic neuron precursor cells for maturation into midbrain-type dopaminergic neurons
Cryopreserved human PSC-derived astrocyte precursor cells for maturation into astrocytes
Cell Culture Media and Supplements (41)
Medium for the maintenance and expansion of cryopreserved human PSC-derived neural progenitor cells