Corning® Matrigel® hESC-Qualified Matrix is an optimized surface for stem cell research and has been widely accepted as an alternative substrate to feeder cells for the culture of human ES and iPS cells (Drukker et al.; Hammerick et al.; Xu et al. 2001 & 2004; Ludwig et al. 2006a & 2006b). It has been qualified to be compatible with mTeSR™1 (Catalog #85850), eliminating the need for time-consuming screening, while providing the reproducibility and consistency essential for human pluripotent stem cell (hPSC) research.
Coupled with feeder-free hPSC maintenance media such as mTeSR™1, mTeSR™ Plus (Catalog #05825), TeSR™-E8™ (Catalog #05990), or TeSR™2 (Catalog #05860), Corning® Matrigel® hESC-Qualified Matrix can successfully maintain human ES and iPS cell lines in the undifferentiated state. These cells retain characteristic hPSC morphology and expression of undifferentiated cell markers such as OCT-3/4, SSEA-3, and TRA-1-60. Corning® Matrigel® hESC-Qualified Matrix is certified to be free of lactose dehydrogenase elevating virus (LDEV/LDHV).
For the lot-specific dilution factor, refer to the Matrigel® Certificate of Analysis, available at www.stemcell.com/coa.
This product is designed for use in the following research area(s) as part of the highlighted workflow stage(s). Explore these workflows to learn more about the other products we offer to support each research area.