Genome Editing

The use of genome editing tools to generate specific changes to the DNA sequence of human pluripotent stem cells (hPSCs), by either introducing or correcting mutations, provides more accurate modeling of human disease when the gene-edited hPSCs are subsequently differentiated into human-derived tissues.

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Cell Culture Media and Supplements (41)

  • CloneR™

    CloneR™

    Defined supplement for single-cell cloning of human ES and iPS cells

Small Molecules (47)

  • New MLN4924

    MLN4924

    Inhibits NEDD8-activating enzyme
  • New NU7026

    NU7026

    NHEJ pathway inhibitor; Inhibits DNA-dependent protein kinase (DNA-PK)
  • New SCR7

    SCR7

    NHEJ pathway inhibitor; inhibits DNA ligase IV
  • New RS-1

    RS-1

    HDR pathway enhancer; Enhances RAD51

Genome Editing and Molecular Tools (48)

Cultureware and General Supplies (42)