The use of genome editing tools to generate specific changes to the DNA sequence of human pluripotent stem cells (hPSCs), by either introducing or correcting mutations, provides more accurate modeling of human disease when the gene-edited hPSCs are subsequently differentiated into human-derived tissues.
Cell Culture Media and Supplements (41)
Small Molecules (47)
Genome Editing and Molecular Tools (48)
Polymerase, buffers, and dNTPs for high-fidelity PCR amplification
For guide RNA generation in CRISPR-Cas9 genome editing
Trans-activating crRNA for guide RNA generation in CRISPR-Cas9 genome editing
Positive control for CRISPR-Cas9 genome editing