· Promotes differentiation of neural progenitor cells from human pluripotent stem cells (Chambers et al.; Kriks et al.).
· Promotes differentiation of neural crest cells from human pluripotent stem cells (Kreitzer et al.).
· Promotes differentiation of anterior foregut endoderm from human and mouse pluripotent stem cell-derived definitive endoderm (Kearns et al.).
· Promotes differentiation of sensory epithelial cells of the inner ear from mouse embryonic stem cells (Koehler et al.).
· Inhibits prostate and breast cancer tumor growth (Balboni et al.; Lee et al.).
· Prevents ovarian cancer cell proliferation (Tsai et al.).
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