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iCell® GlutaNeurons Kit, 01279

Glutamatergic neurons derived from human iPS cells, frozen

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From: 595 USD

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Glutamatergic neurons derived from human iPS cells, frozen
From: 595 USD

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Overview

Understanding basic neuronal physiology and discovering therapeutics to treat neurological disorders has relied heavily on rodent primary cell cultures and animal models. These systems have significant drawbacks in terms of biological relevance, reproducibility, and scalability. iCell® GlutaNeurons provide a relevant, excitatory neuronal model that enables researchers to study human neuronal network development and activity through interrogation and manipulation of relevant pathological pathways involved in seizurogenic and neurodegenerative conditions, thereby providing a new and valuable tool for drug discovery, toxicity testing, and basic research.

iCell® GlutaNeurons, human glutamatergic-enriched cortical neurons derived from induced pluripotent stem (iPS) cells, display typical physiological characteristics and form functional neuronal networks amenable to examination across a number of commonly used assays. These cells providing the following:

• Fully differentiated, ≥ 90% pure population of primarily glutamatergic (excitatory) human neurons
• Long-term viability, demonstrated reproducibility, and availability in commercial quantities
• Rapid formation of excitatory neural networks and functional synapses
• Expression of relevant neurological therapeutic targets and pathways
• Compatible with a wide range of biochemical and cell-based assays including: (1) Cell viability, (2) calcium signaling and (3) neurite outgrowth and retraction
• Electrophysiological applications include: (1) Identification and characterization of network function, (2) higher throughput assessment of compound efficacy for seizure treatment and (3) higher throughput detection of seizurogenic toxicity
• Ease of use - simply thaw and plate

Certain products are only available in select territories. Please contact your local Sales Representative or Product & Scientific Support at techsupport@stemcell.com for further information.
Subtype:
Frozen
Cell Type:
Neurons
Species:
Human
Cell and Tissue Source:
Pluripotent Stem Cells
Donor Status:
Normal

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Product Applications

This product is designed for use in the following research area(s) as part of the highlighted workflow stage(s). Explore these workflows to learn more about the other products we offer to support each research area.

STEMCELL TECHNOLOGIES INC.’S QUALITY MANAGEMENT SYSTEM IS CERTIFIED TO ISO 13485. PRODUCTS ARE FOR RESEARCH USE ONLY AND NOT INTENDED FOR HUMAN OR ANIMAL DIAGNOSTIC OR THERAPEUTIC USES UNLESS OTHERWISE STATED.