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Data and Publications
The biological activity of Human Recombinant BMPR-1A Fc was tested by its ability to inhibit BMP-4-induced alkaline phosphatase production in ATDC-5 cells. Inhibition of BMP-4-induced alkaline phosphatase production was measured using a fluorometric assay method. The EC50 is defined as the effective concentration of the growth factor at which inhibition of alkaline phosphatase production is at 50% of maximum. The EC50 in the above example is 61.5 ng/mL.