Human PSC-Derived Dopaminergic Neurons

Cryopreserved human PSC-derived dopaminergic neuron precursor cells for maturation into midbrain-type dopaminergic neurons

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Dopaminergic Neurons Derived from XCL-1 Human Pluripotent Stem Cells, Male

Human dopaminergic neuron precursors derived from male human pluripotent stem cell line XCL-1

1 x 106 cells
Catalog #70909
849 USD

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Overview

These cryopreserved human pluripotent stem cell (hPSC)-derived dopaminergic neuron precursor cells will generate a population of tyrosine hydroxylase-expressing dopaminergic neurons (> 30% TH-positive dopaminergic neurons, ≥ 80% class III β-tubulin-positive neurons; < 15% GFAP-positive astrocytes) that are functional and can be maintained long-term in culture. Each vial contains ≥ 1 x 10^6 viable precursor cells that can be fully differentiated and matured using the STEMdiff™ Dopaminergic Neuron Maturation Kit (Catalog #08530). These cyopreserved neural cells are convenient, highly consistent, and allow rapid implementation of physiologically relevant hPSC-based models for drug discovery, cell therapy validation, and neuroscientific research.

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Subtype:
Frozen
Cell Type:
Dopaminergic Neurons; Neurons
Species:
Human
Cell and Tissue Source:
Pluripotent Stem Cells
Donor Status:
Normal

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Product Applications

This product is designed for use in the following research area(s) as part of the highlighted workflow stage(s). Explore these workflows to learn more about the other products we offer to support each research area.

Data and Publications

Data

Figure 1. Downstream Differentiation of Neuronal Precursor Cells to Dopaminergic Neurons

hPSC (XCL-1)-derived dopaminergic neurons were matured using the STEMdiff™ Dopaminergic Neuron Maturation Kit, resulting in the formation of dopaminergic neurons that express the neuronal marker class III b-tubulin (red) and the dopaminergic neuronal marker tyrosine hydroxylase (TH; green). Nuclei are counterstained with DAPI. Scale bar= 100 μm.

STEMCELL TECHNOLOGIES INC.’S QUALITY MANAGEMENT SYSTEM IS CERTIFIED TO ISO 13485. PRODUCTS ARE FOR RESEARCH USE ONLY AND NOT INTENDED FOR HUMAN OR ANIMAL DIAGNOSTIC OR THERAPEUTIC USES UNLESS OTHERWISE STATED.