Humanized Mouse Models for Hematopoietic Stem Cell Research: Principles and Pitfalls

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Join our live webinar with Dr. Satiro De Oliveira, Assistant Professor at the University of California, Los Angeles, as he discusses the use of humanized mouse models for hematopoietic stem cell research.

Assistant Professor in Residence
Department of Pediatrics, Hematology and Oncology
University of California, Los Angeles
Live Webinar - Humanized Mouse Models for Hematopoietic Stem Cell Research: Principles and Pitfalls

Wednesday, February 28, 2018 - 10AM PDT | 1PM EDT | 6PM UTC

If you are unable to attend the live webinar, please register and we will send you a link to view the recording when it becomes available.


Topics
  • Generation of humanized mice through engraftment of hematopoietic stem cells into the bone marrow of NOD scid gamma (NSG) mice
  • Benefits and potential pitfalls of humanized mouse models in certain research areas including cancer immunotherapy and gene therapy
  • How humanized mouse models facilitate in vivo studies of hematopoiesis, immune responses and gene transfer technology
Dr. De Oliveira obtained his MD from Faculdade de Medicina de Ribeirao Preto, Universidade de São Paulo, Brazil in 1995. He initially received training in Pediatrics and Pediatric Hematology/Oncology in Brazil, but decided to move to the U.S. to pursue a translational research career. In the US, Dr. De Oliveira subsequently trained in Pediatrics at Woodhull Medical and Mental Health Center, Brooklyn, NY, from 2004 to 2007, and completed his Hematology/Oncology fellowship training at the Children’s Hospital of Los Angeles in 2010, joining UCLA as faculty at the Department of Pediatrics. Dr. De Oliveira’s research interests are cancer immunotherapy and biology of hematopoietic stem cell transplantation, and his long-term goals are to bring cellular therapy approaches to standard clinical practice using hematopoietic stem cell transplantation as a platform for intervention, with a special focus on pediatric patients. He has 21 publications, including high-impact journals such as New England Journal of Medicine, Journal of Clinical Investigation and Immunological Reviews. He has continuously funded his research, having obtained various extramural grants, including the St. Baldrick’s Foundation Scholar Career Development Award, the Hyundai Hope on Wheels Scholar Hope Grant Award and the American Society of Hematology Scholar Award.