Webinar Series: Modeling Human Disease with Pluripotent Stem Cells

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Join us for a live webinar presented by Dr. Andrew Tidball as he discusses current and potential uses of induced pluripotent stem (iPS) cells for modeling epilepsies, how to develop different iPS cell-based model systems, as well as the key advantages and drawbacks of using these model systems.

Dr. Tidball’s current work in the Parent lab involves modeling severe genetic epilepsies in neurons from patient-derived iPS cells. He is interested in drug discovery, particularly in the context of identifying gene-specific therapies optimized for genetic subgroups of epilepsy patients. Dr. Tidball uses gene-editing techniques to generate isogenic controls and “virtual” patient iPS cell lines that he differentiates into neurons for functional analysis.

Dr. Andrew Tidball
Postdoctoral Research Fellow
Jack Parent Lab, University of Michigan
Live Webinar - Modeling Genetic Epilepsies with Induced Pluripotent Stem Cells

Thursday May 25, 2017 - 9AM PDT | 12PM EDT | 5PM UTC

If you are unable to attend the live webinar, please register and we will send you a link to view the recording when it becomes available.


Topics
  • Epilepsy genetics and the use of iPS cells in seizure-related disease research
  • Generation and gene-editing of iPS cells
  • Neuronal differentiation methods and their advantages and drawbacks
  • Outcome assays, including cell autonomous and non-cell autonomous methods
Dr. Tidball obtained his PhD at Vanderbilt University in the lab of Dr. Aaron Bowman where he used iPS cells to study the potential role of environmental metal ion exposure in Huntington’s and Parkinson’s diseases. His overall interests lie in using human iPS cells to model early life neurological disorders. Investigating these diseases provides insights into both potential therapies and important biological functions in the developing brain.

This webinar is part of our webinar series in the Pluripotent Learning Lounge, where key figures in the hPSC field discuss their recent research findings.