Elastase

For digestion of native elastin

Elastase

For digestion of native elastin

From: 224 USD
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For digestion of native elastin
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Product Advantages


  • Digest native elastin effectively

  • Use in combination with other proteinases for successful digestion of fibrous tissue


Overview

Digest native elastin in cell cultures with Elastase. This serine protease is frequently used in combination with other proteases such as collagenase and trypsin to digest fibrous tissue. Elastase consists of a single polypeptide chain of 240 amino acid residues and contains four disulfide bridges (Shotton & Hartley). It is synthesized as a zymogen (proelastase) and then converted to the active form by limited trypsin proteolysis at its N-terminal. Elastase preferentially cleaves the peptide bond of C-terminal neutral, non-aromatic amino acid residues (Schellenberger et al.).
Subtype
Enzymatic
Alternative Names
Elastoproteinase; Lysosomal elastase; Pancreatic elastase I; Pancreatopeptidase E
Cell Type
Epithelial Cells, Myogenic Stem and Progenitor Cells
Species
Human, Mouse, Non-Human Primate, Other, Rat
Application
Cell Culture
Area of Interest
Cancer, Endothelial Cell Biology, Epithelial Cell Biology, Immunology, Stem Cell Biology

Protocols and Documentation

Find supporting information and directions for use in the Product Information Sheet or explore additional protocols below.

Document Type
Product Name
Catalog #
Lot #
Language
Product Name
Elastase
Catalog #
07454, 100-0682, 07453
Lot #
All
Language
English
Document Type
Safety Data Sheet
Product Name
Elastase
Catalog #
07454, 100-0682, 07453
Lot #
All
Language
English

Resources and Publications

Educational Materials (1)