Cancer-sourced leukopaks are an enriched leukapheresis product consisting of a large number of single-donor MNCs. Primary human MNCs are isolated from peripheral blood, leukapheresis, or whole blood samples using density gradient separation or red blood cell lysis and cryopreserved in animal component-free CryoStor® CS10 medium. All fresh and frozen peripheral blood products are obtained from donors diagnosed with colorectal cancer using Institutional Review Board (IRB)-approved consent forms and protocols. Additional documentation to meet institutional requirements is available upon request. Sodium heparin (Na-Hep), ethylenediaminetetraacetic acid (EDTA), or acid-citrate-dextrose solution A (ACDA) is added during collection as an anticoagulant.
Contact firstname.lastname@example.org if high-resolution HLA typing (Class I and Class II alleles and CMV status) is required or for donor specifications (BMI category, smoking status, ethnicity, etc.). Donors are screened for HIV-1, HIV-2, hepatitis B, and hepatitis C. Certain products are only available in select territories. For more information, browse frequently asked questions (FAQs) on primary cells.
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