Collagenase Type II

For digestion of native collagen fibrils

Collagenase Type II

For digestion of native collagen fibrils

From: 103 USD
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For digestion of native collagen fibrils
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Product Advantages



  • Use in a variety of cell and tissue types


Overview

Digest native collagen fibrils in connective tissues with Collagenase Type II, sourced from Clostridium histolyticum. Collagenase preparations contain the activity of several proteases, including collagenase, caseinase, clostripain, and trypsin (Kessler & Yaron). With high levels of protease activity, especially clostripain, Collagenase Type II has been used for the digestion of many tissues and cell types, including lung (You & Brody; Comhair et al.), kidney (Valente et al.), liver (Linghor et al.), thymus (Vandenabeele et al.), endothelial cells (Patel et al.) and mesenchymal stem cells (Steigman & Fauza).
Subtype
Enzymatic
Alternative Names
Clostridium histolyticum collagenase; Collagenase 2; Collagenase Type 2; Collagenase II
Cell Type
Endothelial Cells, Hepatic Cells, Mesenchymal Stem and Progenitor Cells, T Cells, CD4+
Species
Human, Mouse, Non-Human Primate, Other, Rat
Application
Cell Culture
Area of Interest
Cancer, Endothelial Cell Biology, Epithelial Cell Biology, Immunology, Stem Cell Biology

Protocols and Documentation

Find supporting information and directions for use in the Product Information Sheet or explore additional protocols below.

Document Type
Product Name
Catalog #
Lot #
Language
Catalog #
07419, 07418, 100-0678
Lot #
All
Language
English
Document Type
Safety Data Sheet
Catalog #
07419, 07418, 100-0678
Lot #
All
Language
English

Applications

This product is designed for use in the following research area(s) as part of the highlighted workflow stage(s). Explore these workflows to learn more about the other products we offer to support each research area.

Resources and Publications

Educational Materials (1)