You searched for: 18780
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WallchartAntigen Processing and Presentation
Overview of the mechanisms by which antigens are processed and presented to T cells -
WallchartFrequencies and Percentages of Mouse Immune Cell Types
List of the frequencies of over 25 immune cell types in C57BL/6 mice -
0:57VideoEasyEights™: Faster and Easier Multiple Sample Cell Isolations
Publish Date: September 22, 2014 Views: 0 -
1:57 -
1:13VideoThe EasySep™ Pour-off: A Simple and Effective Way to Isolate Cells
Publish Date: October 02, 2009 Views: 0 -
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WallchartHuman Immune Cytokines
Infographic of key cytokines for expansion, differentiation and characterization of major immune cell types -
Safety Data Sheet (SDS)
DX21015-SDS_2_0_0.pdf
Catalog #Product Name:18765EasySep™ Mouse CD4+CD62L+ T Cell Isolation Kit18780RFRoboSep™ Mouse CD11c Positive Selection Kit II18952EasySep™ Mouse CD4 Positive Selection Kit II18952RFRoboSep™ Mouse CD4 Positive Selection Kit II19709EasySep™ Mouse Custom Enrichment Kit19709RFRoboSep™ Mouse Custom Enrichment Kit with Filter Tips19762EasySep™ Mouse Neutrophil Enrichment Kit19844EasySep™ Mouse Pan-B Cell Isolation Kit19851EasySep™ Mouse T Cell Isolation Kit19853EasySep™ Mouse CD8+ T Cell Isolation Kit19860EasySep™ Mouse Streptavidin RapidSpheres™ Isolation Kit19762RFRoboSep™ Mouse Neutrophil Enrichment Kit with Filter Tips19765EasySep™ Mouse Naïve CD4+ T Cell Isolation Kit19765RFRoboSep™ Mouse Naïve CD4+ T Cell Isolation Kit19767EasySep™ Mouse Memory CD4+ T Cell Isolation Kit19767RFRoboSep™ Mouse Memory CD4+ T Cell Isolation Kit19844RFRoboSep™ Mouse Pan-B Cell Isolation Kit19848RFRoboSep™ Mouse Pan-Naïve T Cell Isolation Kit19851RFRoboSep™ Mouse T Cell Isolation Kit19852EasySep™ Mouse CD4+ T Cell Isolation Kit19852RFRoboSep™ Mouse CD4+ T Cell Isolation Kit19853RFRoboSep™ Mouse CD8+ T Cell Isolation Kit19854EasySep™ Mouse B Cell Isolation Kit19854RFRoboSep™ Mouse B Cell Isolation Kit19856EasySep™ Mouse Hematopoietic Progenitor Cell Isolation Kit19856RFRoboSep™ Mouse Hematopoietic Progenitor Cell Isolation Kit19858EasySep™ Mouse Naïve CD8+ T Cell Isolation Kit19858RFRoboSep™ Mouse Naïve CD8+T Cell Isolation Kit19860RFRoboSep™ Mouse Streptavidin RapidSpheres™ Isolation Kit19861EasySep™ Mouse Monocyte Isolation Kit19861RFRoboSep™ Mouse Monocyte Isolation Kit18780EasySep™ Mouse CD11c Positive Selection Kit II18781EasySep™ Mouse CD11c Positive Selection Kit II with Spleen Dissociation Medium18970EasySep™ Mouse CD11b Positive Selection Kit II18970RFRoboSep™ Mouse CD11b Positive Selection Kit II19848EasySep™ Mouse Pan-Naïve T Cell Isolation Kit19849EasySep™ Mouse/Human Chimera Isolation Kit18781RFRoboSep™ Mouse CD11c Positive Selection Kit II with Spleen Dissociation Medium18783EasySep™ Mouse CD4+CD25+ Regulatory T Cell Isolation Kit II18783RFRoboSep™ Mouse CD4+CD25+ Regulatory T Cell Isolation Kit II17656EasySep™ Release Mouse PE Positive Selection Kit19842EasySep™ Mouse ILC2 Enrichment Kit100-0107EasySep™ Release Human CD45 Positive Selection Kit for Humanized Mice100-0109RoboSep™ Release Human CD45 Positive Selection Kit for Humanized Mice100-0033EasySep™ Release Mouse APC Positive Selection Kit -
Safety Data Sheet (SDS)
DX22395-SDS_1_0_0.pdf
Catalog #Product Name:17851EasySep™ Human CD3 Positive Selection Kit II17851RFRoboSep™ Human CD3 Positive Selection Kit II17852EasySep™ Human CD4 Positive Selection Kit II17852RFRoboSep™ Human CD4 Positive Selection Kit II17853EasySep™ Human CD8 Positive Selection Kit II17853RFRoboSep™ Human CD8 Positive Selection Kit II17854EasySep™ Human CD19 Positive Selection Kit II17854RFRoboSep™ Human CD19 Positive Selection Kit II17855EasySep™ Human CD56 Positive Selection Kit II17855RFRoboSep™ Human CD56 Positive Selection Kit II17858EasySep™ Human CD14 Positive Selection Kit II17858RFRoboSep™ Human CD14 Positive Selection Kit II17896EasySep™ Human Cord Blood CD34 Positive Selection Kit II17896RFRoboSep™ Human CB CD34 Positive Selection Kit II18063EasySep™ Human CD4+CD127lowCD25+ Regulatory T Cell Isolation Kit18765EasySep™ Mouse CD4+CD62L+ T Cell Isolation Kit18765RFRoboSep™ Mouse CD4+CD62L+ T Cell Isolation Kit18780RFRoboSep™ Mouse CD11c Positive Selection Kit II18782EasySep™ Mouse CD25 Regulatory T Cell Positive Selection Kit18782RFRoboSep™ Mouse CD25 Regulatory T cell Positive Selection Kit18951EasySep™ Mouse CD90.2 Positive Selection Kit II18952EasySep™ Mouse CD4 Positive Selection Kit II18952RFRoboSep™ Mouse CD4 Positive Selection Kit II18953EasySep™ Mouse CD8a Positive Selection Kit II18953RFRoboSep™ Mouse CD8a Positive Selection Kit II18954EasySep™ Mouse CD19 Positive Selection Kit II15086Complete Kit for Human Whole Blood CD34+ Cells15086RFRoboSep™ Complete Kit for Human Whole Blood CD34+ Cells05925CD34+ Progenitor Reprogramming Kit17897EasySep™ Human Cord Blood CD34 Positive Selection Kit III17897RFRoboSep™ Human Cord Blood CD34 Positive Selection Kit III18780EasySep™ Mouse CD11c Positive Selection Kit II18781EasySep™ Mouse CD11c Positive Selection Kit II with Spleen Dissociation Medium18970EasySep™ Mouse CD11b Positive Selection Kit II18970RFRoboSep™ Mouse CD11b Positive Selection Kit II18781RFRoboSep™ Mouse CD11c Positive Selection Kit II with Spleen Dissociation Medium18783EasySep™ Mouse CD4+CD25+ Regulatory T Cell Isolation Kit II18957EasySep™ Mouse CD138 Positive Selection Kit18958EasySep™ Mouse CD90.1 Positive Selection Kit18990EasySep™ Anti-Rat IgG2a Positive Selection Kit18992EasySep™ Anti-Rat IgG2b Positive Selection Kit18994EasySep™ Anti-Rat IgM Positive Selection Kit18783RFRoboSep™ Mouse CD4+CD25+ Regulatory T Cell Isolation Kit II18957RFRoboSep™ Mouse CD138 Positive Selection Kit18958RFRoboSep™ Mouse CD90.1 Positive Selection Kit18990RFRoboSep™ Anti-Rat IgG2a Positive Selection Kit18992RFRoboSep™ Anti-Rat IgG2b Positive Selection Kit18994RFRoboSep™ Anti-Rat IgM Positive Selection Kit18651EasySep™ Human CD15 Positive Selection Kit17887EasySep™ Human Whole Blood and Bone Marrow CD138 Positive Selection Kit II17887RFRoboSep™ Human Whole Blood and Bone Marrow CD138 Positive Selection Kit II17878EasySep™ HLA Chimerism Buffy Coat CD14 Positive Selection Kit17878RFRoboSep™ HLA Chimerism Buffy Coat CD14 Positive Selection Kit17663EasySep™ Human Biotin Positive Selection Kit II17663RFRoboSep™ Human Biotin Positive Selection Kit II17664EasySep™ Human PE Positive Selection Kit II17664RFRoboSep™ Human PE Positive Selection Kit II17684EasySep™ PE Positive Selection Kit II17684RFRoboSep™ PE Positive Selection Kit II17698EasySep™ "Do-It-Yourself" Positive Selection Kit II17698RFRoboSep™ "Do-It-Yourself" Positive Selection Kit II17699EasySep™ Human "Do-It-Yourself" Positive Selection Kit II17699RFRoboSep™ Human "Do-It-Yourself" Positive Selection Kit II17661EasySep™ Human APC Positive Selection Kit II17661RFRoboSep™ Human APC Positive Selection Kit II17662EasySep™ Human FITC Positive Selection Kit II17662RFRoboSep™ Human FITC Positive Selection Kit II17665EasySep™ Mouse Biotin Positive Selection Kit II17665RFRoboSep™ Mouse Biotin Positive Selection Kit II17666EasySep™ Mouse PE Positive Selection Kit II17666RFRoboSep™ Mouse PE Positive Selection Kit II17667EasySep™ Mouse APC Positive Selection Kit II17667RFRoboSep™ Mouse APC Positive Selection Kit II17668EasySep™ Mouse FITC Positive Selection Kit II17668RFRoboSep™ Mouse FITC Positive Selection Kit II17681EasySep™ APC Positive Selection Kit II17681RFRoboSep™ APC Positive Selection Kit II17682EasySep™ FITC Positive Selection Kit II17682RFRoboSep™ FITC Positive Selection Kit II17683EasySep™ Biotin Positive Selection Kit II17683RFRoboSep™ Biotin Positive Selection Kit II17888EasySep™ HLA Chimerism Whole Blood CD4 Positive Selection Kit17888RFRoboSep™ HLA Chimerism Whole Blood CD4 Positive Selection Kit17846EasySep™ Human EpCAM Positive Selection Kit II17846RFRoboSep™ Human EpCAM Positive Selection Kit II17849EasySep™ Human CD271 Positive Selection Kit II17856EasySep™ Human CD34 Positive Selection Kit II17856RFEasySep™ Human CD34 Positive Selection Kit II17879EasySep™ Human Whole Blood CD34 Positive Selection Kit II17879RFRoboSep™ Human Whole Blood CD34 Positive Selection Kit II17893EasySep™ Human Myeloid Positive Selection Kit II17893RFRoboSep™ Human Myeloid Positive Selection Kit II17965EasySep™ Human PSC-Derived Cardiomyocyte Enrichment Kit18945EasySep™ Mouse CD45 Positive Selection Kit100-0350EasySep™ Mouse TIL (CD45) Positive Selection Kit -
Product Information Sheet (PIS)
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Product Information Sheet (PIS)
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Product Information Sheet (PIS)
28007-PIS_3_3_1.pdf
Catalog #LotLanguageProduct Name:18780RFAllENRoboSep™ Mouse CD11c Positive Selection Kit II18780AllENEasySep™ Mouse CD11c Positive Selection Kit II18781AllENEasySep™ Mouse CD11c Positive Selection Kit II with Spleen Dissociation Medium18781RFAllENRoboSep™ Mouse CD11c Positive Selection Kit II with Spleen Dissociation Medium -
ReferenceLiu T-T et al. (MAY 2016) Journal of Immunology
LSm14A Plays a Critical Role in Antiviral Immune Responses by Regulating MITA Level in a Cell-Specific Manner.
Viral infection triggers induction of antiviral cytokines and effectors, which are critical mediators of innate antiviral immune response. It has been shown that the processing body-associated protein LSm14A is involved in the induction of antiviral cytokines in cell lines but in vivo evidence is lacking. By generating LSm14A-deficient mice, in this study, we show that LSm14A plays a critical and specific role in the induction of antiviral cytokines in dendritic cells (DCs) but not in macrophages and fibroblasts. Induction of antiviral cytokines triggered by the DNA viruses HSV-1 and murid herpesvirus 68 and the RNA virus vesicular stomatitis virus but not Sendai virus was impaired in Lsm14a(-/-) DCs, which is correlated to the functions of the adaptor protein MITA/STING in the antiviral signaling pathways. LSm14A deficiency specifically downregulated MITA/STING level in DCs by impairing its nuclear mRNA precursor processing and subsequently impaired antiviral innate and adaptive immune responses. Our findings reveal a nuclear mRNA precursor processing and cell-specific regulatory mechanism of antiviral immune responses. View PublicationCatalog #:Product Name:18758EasySep™ Mouse CD11c Positive Selection Kit18780EasySep™ Mouse CD11c Positive Selection Kit II -
ReferenceXu MM et al. (AUG 2017) Immunity 47 2 363--373.e5
Dendritic Cells but Not Macrophages Sense Tumor Mitochondrial DNA for Cross-priming through Signal Regulatory Protein α Signaling.
Inhibition of cytosolic DNA sensing represents a strategy that tumor cells use for immune evasion, but the underlying mechanisms are unclear. Here we have shown that CD47-signal regulatory protein α (SIRPα) axis dictates the fate of ingested DNA in DCs for immune evasion. Although macrophages were more potent in uptaking tumor DNA, increase of DNA sensing by blocking the interaction of SIRPα with CD47 preferentially occurred in dendritic cells (DCs) but not in macrophages. Mechanistically, CD47 blockade enabled the activation of NADPH oxidase NOX2 in DCs, which in turn inhibited phagosomal acidification and reduced the degradation of tumor mitochondrial DNA (mtDNA) in DCs. mtDNA was recognized by cyclic-GMP-AMP synthase (cGAS) in the DC cytosol, contributing to type I interferon (IFN) production and antitumor adaptive immunity. Thus, our findings have demonstrated how tumor cells inhibit innate sensing in DCs and suggested that the CD47-SIRPα axis is critical for DC-driven antitumor immunity. View PublicationCatalog #:Product Name:18780EasySep™ Mouse CD11c Positive Selection Kit II19853EasySep™ Mouse CD8+ T Cell Isolation Kit70025Human Peripheral Blood Mononuclear Cells, Frozen -
ReferenceMaldonado M et al. (MAY 2016) Advanced Healthcare Materials 5 12 1408--1412
Enhanced Lineage-Specific Differentiation Efficiency of Human Induced Pluripotent Stem Cells by Engineering Colony Dimensionality Using Electrospun Scaffolds
Electrospun scaffolds with varied stiffness promote distinct colony morphology of human induced pluripotent stem cells, which affects their subsequent differentiation. On soft scaffolds, induced pluripotent stem cells develop 3D colonies due to the pliability of the electrospun fibrous networks, leading to greater differentiation tendency to ectodermal lineage. View PublicationCatalog #:Product Name:05850mTeSR™185850mTeSR™1