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product
ProstaCult™ Medium (Mouse) for mouse prostate epithelial cell culture
background
The prostate is composed of 4 lobes, with each lobe composed of a series of branching ducts, which are composed of 3 lineages of epithelial cells: basal, luminal and neuroendocrine. Evidence is now emerging that prostatic epithelium is composed of a hierarchy of cells that spans from prostate stem cells (PSCs) to progenitor cells to terminally differentiated cells.1-3 Recent reports have also demonstrated that prostate tumours are also arranged as a hierarchy and that cancer stem cells can be prospectively isolated.4,5 Key to the identification and characterization of these different cell types has been the use of cell purification strategies such as fluorescence-activated cell sorting and/or immunomagnetic enrichment to isolate phenotypically distinct subsets of prostate cells and the use of robust quantitative functional assays to determine the growth and differentiation properties of these cells at the clonal level.
products for dissociation, enrichment and cell culture
STEMCELL Technologies offers a variety of products for the dissociation and culture of mouse prostate tissue. These products include: Mouse prostate epithelial cells can be isolated for analysis and characterization by dissociating tissues into single cell suspension using a variety of enzymes such as · Enzymes such as Collagenase/Hyaluronidase, Dispase, Trypsin and DNase I for the dissociation of mouse prostate tissue. · ProstaCult™ Medium (Mouse) for the culture of mouse prostate epithelial cells.
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