CD10 Antibody, Clone FR4D11

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Mouse Monoclonal Antibody to Human CD10

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  • Vial label for Anti-Human CD10 (Clone FR4D11) 100 µg
Vial label for Anti-Human CD10 (Clone FR4D11) 100 µg
CD10, also known as Common Acute Lymphocytic Leukemia Antigen (CALLA), is a cell surface enzyme with neutral metalloendopeptidase activity which inactivates a variety of biologically active peptides. CD10 is expressed on the cells of lymphoblastic, Burkitt's, and follicular germinal center lymphomas, immature B cells with in adult bone marrow and on cells from patients with chronic myelocytic leukemia (CML). CD10 is also present on breast myoepithelial cells, bile canaliculi, fibroblasts, with especially high expression on the brush border of kidney and gut epithelial cells. Most notably, CD10 was reported to mark human mammary bipotent progenitors.
Product Name Description Catalog # Size Price Quantity
CD10 Antibody, Clone FR4D11 Mouse monoclonal antibody to human CD10 01431 100 µg 153.00 USD      
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Recommended for:
• Cell Separation
• Immunohistochemistry
Intended Use Statement: For Research Use Only. Not for Therapeutic or Diagnostic Use.
Contains:
0.1 mg in 0.1 mL (1 mg/mL) phosphate buffered saline
Immunogen: Raji (Burkitt’s lymphoma) cells
Clone Name: FR4D11
Isotype: IgG1
Product Type: Antibodies
Antibody Type: Primary antibodies
Application: Cell isolation, Immunohistochemistry
Area of Interest: Mammary cell research
Cell Type: Mammary epithelial cells
Clonality: Monoclonal
Conjugation: Unconjugated
Host Species: Mouse
Species Reactivity: Human

Procedures and instruction manuals:

Educational resources:

MSDS:

Background References:

  1. Maria Isabel D Rossi et al. B lymphopoiesis is active throughout human life, but there are developmental age-related changes.Blood 101 (2) 576-584 (January 15, 2003)
  2. A J Turner et al. The neprilysin (NEP) family of zinc metalloendopeptidases: genomics and function.Bioessays 23 (3) 261-269 (March 2001)
  3. J N Baraniuk et al. Localization of neutral endopeptidase (NEP) mRNA in human bronchi.Eur Respir J 8 (9) 1458-1464 (September 1995)
  4. M J O'Hare et al. Characterization in vitro of luminal and myoepithelial cells isolated from the human mammary gland by cell sorting.Differentiation 46 (3) 209-221 (April 1991)
  5. P S Rudland et al. Immunocytochemical identification of cell types in human mammary gland: variations in cellular markers are dependent on glandular topography and differentiation.J Histochem Cytochem 37 (7) 1087-1100 (July 1989)
  6. M A Shipp et al. Molecular cloning of the common acute lymphoblastic leukemia antigen (CALLA) identifies a type II integral membrane protein.Proc Natl Acad Sci U S A 85 (13) 4819-4823 (July 1988)
  7. B A Gusterson et al. Identification of myoepithelial cells in human and rat breasts by anti-common acute lymphoblastic leukemia antigen antibody A12.J Natl Cancer Inst 77 (2) 343-349 (August 1986)
  8. R A Newman et al. The biochemical characterization of a cell surface antigen associated with acute lymphoblastic leukemia and lymphocyte precursors.J Immunol 126 (5) 2024-2030 (May 1981)
  9. S E Sallan et al. Cell surface antigens: prognostic implications in childhood acute lymphoblastic leukemia.Blood 55 (3) 395-402 (March 1980)
  10. J M Pesando et al. Leukemia-associated antigens in ALL.Blood 54 (6) 1240-1248 (December 1979)

Product Name

Description

Catalog #
EasySep® Human CD10 Positive Selection Kit Immunomagnetic Positive Selection Kit 18358

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