Alpha-Internexin Antibody

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Rabbit Polyclonal Antibody to α-Internexin



  • Vial label for Anti-α-Internexin  Rabbit Polyclonal Antibody 100 µL
Vial label for Anti-α-Internexin Rabbit Polyclonal Antibody 100 µL
Alpha-internexin is a ~66 kDa Class IV intermediate filament. It is related to but distinct from the better known neurofilament triplet proteins, NF-L, NF-M and NF-H, and has similar protein sequence motifs and intron organization. It is expressed in large amounts early during neuronal development, but is downregulated in many neurons as development proceeds. Many classes of mature neurons contain α-internexin in addition to neurofilament proteins NF-L, NF-M and NF-H. In some mature neurons α-internexin is the only neurofilament subunit expressed. The very early developmental expression of α-internexin means its presence can be used an early and convenient diagnostic feature of neuronal progenitors cells and other cells committed to the neuronal lineage. Recent studies indicate that there is a marked up-regulation of α-internexin during neuronal regeneration. This rabbit polyclonal antibody detects α-internexin from human, rat, mouse, cat and all other species tested to date.
Product Name Description Catalog # Size Price Quantity
alpha-Internexin Antibody Rabbit polyclonal antibody to α-Internexin 01442 100 µL 309.00 USD      
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Intended Use Statement: For Research Use Only. Not for Therapeutic or Diagnostic Use.
Contains:
Rabbit polyclonal antiserum
Immunogen: Recombinant a-internexin expressed in and purified from E. coli.
Product Type: Antibodies
Antibody Type: Primary antibodies
Application: Immunoblotting
Area of Interest: Neuroscience
Cell Type: Neural stem & progenitor cells, Neurons
Clonality: Polyclonal
Conjugation: Unconjugated
Popular Product Line: NeuroCult
Research Area: Neuroscience
Species Reactivity: Human, Mouse, Rat

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Description

Catalog #

Alpha-Internexin Antibody, Clone 2E3 Mouse Monoclonal Antibody to α-Internexin 01443
Alpha-Internexin Antibody, Clone 1D2 Mouse Monoclonal Antibody to α-Internexin 01444