CD32 Antibody, Clone IV.3

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Mouse Monoclonal Antibody to Human CD32, Clone IV.3

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  • Vial label for Anti-Human CD32 (Clone IV.3) Mouse Monoclonal Antibody 0.1 mg
Vial label for Anti-Human CD32 (Clone IV.3) Mouse Monoclonal Antibody 0.1 mg
CD32 (FcγRII) is a 40,000 D receptor for the Fc region of Immunoglobulin G (IgG). CD32 is encoded by three genes, A, B, and C, and is expressed as 6 protein isoforms, IIa1, IIa2, IIb1, IIb2, IIb3 and IIc. The Ila isoform is expressed on platelets, granulocytes and weakly on B cells, while the Ilb isoform is expressed on B cells and the Ilc isoform is expressed on NK cells. All isoforms are expressed on monocytes/macrophages. CD32 binds weakly to the Fc portion of monomeric IgG, but efficiently to IgG aggregates and immune complexes. The Fc/FcR interactions may result in nonspecific staining in antibody-based detection and cell separation experiments. This mouse monoclonal antibody was generated in a CAF1 mouse immunized with the K562 cell line and binds to CD32 (FcγRII) on human cells. In flow cytometry, this antibody can be used to stain CD32+ cells or to block undesired CD32/IgG Fc interactions. In cell separation, it can be used to block nonspecific antibody binding to monocytes and other FcγRII+ cells in positive selection or depletion of FcγRII- cells.
Product Name Description Catalog # Size Price Quantity
CD32 Antibody, Clone IV.3 Mouse monoclonal antibody to human CD32 01470 100 µg 185.00 USD      
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Intended Use Statement: For Research Use Only. Not for Therapeutic or Diagnostic Use.
Contains:
0.1 mg in 0.1 mL (1 mg/mL) phosphate buffered saline
Clone Name: IV.3
Isotype: IgG2b
Product Type: Antibodies
Cell Type: Monocytes
Area of Interest: Immunology
Antibody Type: Primary antibodies
Research Area: Immunology
Application: Cell isolation, Flow cytometry
Species Reactivity: Human
Conjugation: Unconjugated
Clonality: Monoclonal
Host Species: Mouse

Procedures and instruction manuals:

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Product Name

Description

Catalog #
CD32 Antibody, Clone FLI8.26 Mouse Monoclonal Antibody to Human CD32 01435
CD32 Antibody, Clone FLI8.26, FITC-Conjugated Mouse Monoclonal Antibody to Human CD32 - FITC Conjugated 10425
CD32 Antibody, Clone IV.3, FITC-Conjugated Mouse Monoclonal Antibody to Human CD32 - FITC Conjugated 10433

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