CD54 Antibody, Clone YN1/1.7.4

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Rat Monoclonal Antibody to Mouse CD54



  • Vial label for Anti-Mouse CD54 (Clone YN1/1.7.4) 100 µL
Vial label for Anti-Mouse CD54 (Clone YN1/1.7.4) 100 µL
CD54 (ICAM-1) is a 95 kDa member of the Ig superfamily. It is expressed by lymphocytes, macrophages and dendritic cells, as well as by vascular endothelium and high endothelial venules. ICAM-1 is an important intercellular adhesion molecule that contributes to T-cell/T-cell, T-cell/B-cell and T-cell/target cell interactions via binding of LFA-1 and Mac-1 (CD11a/CD18 and CD11b/CD18 complexes, respectively) and participates in lymphocyte tracking and T-cell signal transduction events. It is also the receptor for the major group of rhinoviruses. The YN1/1.7.4 monoclonal antibody efficiently blocks the binding of ICAM-1 to LFA-1 and Mac-1 and inhibits ICAM-1 mediated functions including cell-cell adhesion, antigen presentation to T-cells and leukocyte migration to inflammatory tissues.
Product Name Description Catalog # Size Price Quantity
CD54 Antibody, Clone YN1/1.7.4 Rat monoclonal antibody to mouse CD54 01503 100 µg 153.00 USD      
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Recommended for:
• Cell Separation
• Flow Cytometry
• Immunoprecipitation
• Immunoblotting
Intended Use Statement: For Research Use Only. Not for Therapeutic or Diagnostic Use.
Contains:
0.1 mg in 0.1 mL (1 mg/mL) phosphate buffered saline
Immunogen: Mouse NS1 cells
Clone Name: YN1/1.7.4
Isotype: IgG2b,k
Product Type: Antibodies
Cell Type: Granulocytes & subsets
Area of Interest: Immunology
Antibody Type: Primary antibodies
Research Area: Immunology
Application: Cell isolation, Flow cytometry, Immunoblotting
Species Reactivity: Mouse
Conjugation: Unconjugated
Clonality: Monoclonal
Host Species: Rat

Procedures and instruction manuals:

MSDS:

Product Name

Description

Catalog #

CD54 Antibody, Clone YN1/1.7.4, Biotin-Conjugated Rat Monoclonal Antibody to Mouse CD54 - Biotin Conjugated 10151
CD54 Antibody, Clone YN1/1.7.4, FITC-Conjugated Rat Monoclonal Antibody to Mouse CD54 - FITC Conjugated 10715