BMP-4, Human, Recombinant

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Bone Morphogenetic Protein-4

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  • Vial label for rh BMP-4 10 µg
Vial label for rh BMP-4 10 µg
BMP-4 (Bone Morphogenetic Protein-4) is a member of the highly conserved transforming growth factor-β (TGF-β) superfamily. BMPs have been shown to be key regulators of embryogenesis and are known to play a role in the growth and differentiation of various cell types, including embryonic stem cells (ESCs), induced pluripotent stem cells (iPSCs), mesenchymal cells, epithelial cells, hematopoietic cells, and neuronal cells. The mature recombinant human BMP-4 is a disulfide-linked homodimeric protein consisting of two 116 amino acid residue subunits, and is generated by the proteolytic removal of the signal peptide and propeptides. The monomer has a calculated molecular mass of approximately 13 kDa, but migrates as an approximately 22 kDa protein under reducing conditions in SDS-PAGE due to glycosylation.
Product Name Description Catalog # Size Price Quantity
BMP-4, Human, Recombinant Bone morphogenetic protein-4 02524 10 µg 571.00 USD      
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Intended Use Statement: For Research Use Only. Not for Therapeutic or Diagnostic Use.
Purity: >95%
Activity: The ED50 on ATDC5 chondrogenic cells is 10 - 30 ng/mL (please refer to PIS)
Expression System: NS0 Cell Line
Product Type: Cytokines
Application: Maintenance
Cell Type: Embryonic stem cells & iPS cells
Species: Human
Species Cross Reactivity: Mouse

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