bFGF (Carrier-Free), Human, Recombinant

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Basic Fibroblast Growth Factor (Carrier-Free)

Vial label for rh bFGF (Carrier Free) 25 ug

Basic Fibroblast Growth Factor (bFGF) is a member of the FGF family. It has been shown to support the maintenance of undifferentiated human embryonic stem cells and stimulate the proliferation of all cells of mesodermal origin, and many cells of neuroectodermal, ectodermal and endodermal origin, including fibroblasts, endothelial cells, astrocytes, oligodendrocytes, neuroblasts, keratinocytes, osteoblasts, smooth muscle cells and melanocytes. bFGF is a chemotactic and mitogenic agent for endothelial cells in vitro and induces neural differentiation, survival and regeneration. It has been shown to be crucial in modulating embryonic development and differentiation. These observations from in vitro functions of bFGF suggest it may play a role in the modulation of angiogenesis, tissue repair, embryonic development and neuronal function in vivo. N-terminal extensions of bFGF affect its localization compartments but do not affect its biological activity. The 157 amino acid residue recombinant protein has a predicted molecular mass of approximately 17.4 kDa.

Product Name	Description	Catalog #	Size	Price	Quantity
bFGF (Carrier-Free), Human, Recombinant	Basic fibroblast growth factor	02654	25 µg	349.00 USD		Save Item

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Intended Use Statement:	For Research Use Only. Not for Therapeutic or Diagnostic Use.
Contains:	Supplied as a 0.2 µm filtered solution in 20 mM Tris and 1 M NaCl (pH 7.0)
Purity:	>97%
Activity:	The ED50 on NR6R-3T3 fibroblasts is 0.1 - 0.15 ng/mL (please please refer to PIS for details)
Expression System:	E. coli
Product Type:	Cytokines
Cell Type:	Embryonic stem cells & iPS cells, Mammary epithelial cells, Neural stem & progenitor cells
Species:	Human