NeuroCult® Basal Medium (Mouse)

Procedures and instruction manuals:

•  MANUAL: In Vitro Proliferation and Differentiation of Mouse Neural Stem Cells and Progenitor Cells Using NeuroCult™
•  PRODUCT INFORMATION SHEET - 05700, Lot# All:29571-PIS_2_0_0.pdf

Educational resources:

•  BROCHURE: Neural Stem Cells: Standardized Media and Reagents
•  BROCHURE: NeuroCult™ Reagents for Brain Tumor Stem Cell Research
•  SCIENTIFIC POSTER: Optimized reagents for the repoducible expansion and differentiation of adult and embryonic mouse neural stem cells in neurosphere and adherent cultures
•  VIDEO: NeuroCult™ Proliferation Media
•  WEBINAR: Neural Stem Cell Culture Systems - Neurosphere vs. Adherent Monolayer Culture
•  TECH BULLETIN: Cryopreserving Neurospheres

MSDS:

•  05700-MSDS.pdf

This product has been used in:

1. Massimo Squatrito et al. Loss of ATM/Chk2/p53 Pathway Components Accelerates Tumor Development and Contributes to Radiation Resistance in Gliomas.Cancer Cell 18 (6) 619-629 (December 14, 2010)
2. Hongwu Zheng et al. PLAGL2 regulates Wnt signaling to impede differentiation in neural stem cells and gliomas.Cancer Cell 17 (5) 497-509 (May 18, 2010)
3. Areechun Sotthibundhu et al. Abeta(1-42) stimulates adult SVZ neurogenesis through the p75 neurotrophin receptor.Neurobiol Aging 30 (12) 1975-1985 (December 2009)
4. Evan Elliott et al. BAG-1 is preferentially expressed in neuronal precursor cells of the adult mouse brain and regulates their proliferation in vitro.FEBS Lett 583 (1) 229-234 (January 5, 2009)
5. Celine Mathieu et al. Endothelial cell-derived bone morphogenetic proteins control proliferation of neural stem/progenitor cells.Molecular and cellular neurosciences 38 (4) 569-577 (August 2008)
6. Yun Li et al. TrkB regulates hippocampal neurogenesis and governs sensitivity to antidepressive treatment.Neuron 59 (3) 399-412 (August 14, 2008)
7. Zeng-Jie Yang et al. Medulloblastoma can be initiated by deletion of Patched in lineage-restricted progenitors or stem cells.Cancer Cell 14 (2) 135-145 (August 12, 2008)
8. Sharon A Louis et al. Enumeration of neural stem and progenitor cells in the neural colony-forming cell assay.Stem Cells 26 (4) 988-996 (April 2008)
9. Yoko Ishii et al. Characterization of neuroprogenitor cells expressing the PDGF beta-receptor within the subventricular zone of postnatal mice.Mol Cell Neurosci 37 (3) 507-518 (March 2008)
10. Karine Sii-Felice et al. Fanconi DNA repair pathway is required for survival and long-term maintenance of neural progenitors.EMBO J 27 (5) 770-781 (March 5, 2008)
11. Guillaume Grenier et al. Resident endothelial precursors in muscle, adipose, and dermis contribute to postnatal vasculogenesis.Stem Cells 25 (12) 2006-0795 (September 6, 2007)
12. Kaylene M Young et al. Subventricular zone stem cells are heterogeneous with respect to their embryonic origins and neurogenic fates in the adult olfactory bulb.J Neurosci 27 (31) 8286-8296 (August 1, 2007)
13. Jian-Mei Li et al. Angiotensin II-induced neural differentiation via angiotensin II type 2 (AT2) receptor-MMS2 cascade involving interaction between AT2 receptor-interacting protein and Src homology 2 domain-containing protein-tyrosine phosphatase 1.Mol Endocrinol 21 (2) 499-511 (February 2007)
14. Eiji Mizutani et al. Developmental ability of cloned embryos from neural stem cells.Reproduction 132 (6) 849-857 (December 2006)
15. Sung-Jo Kim et al. Palmitoyl-protein thioesterase-1 deficiency leads to the activation of caspase-9 and contributes to rapid neurodegeneration in INCL.Hum Mol Genet 15 (10) 1580-1586 (May 15, 2006)
16. Jun Udagawa et al. The role of leptin in the development of the cerebral cortex in mouse embryos.Endocrinology 147 (2) 647-658 (February 2006)
17. Turhan Coksaygan et al. Neurogenesis in Talpha-1 tubulin transgenic mice during development and after injury.Exp Neurol 197 (2) 475-485 (February 2006)
18. Satoshi Kishigami et al. Significant improvement of mouse cloning technique by treatment with trichostatin A after somatic nuclear transfer.Biochem Biophys Res Commun 340 (1) 183-189 (February 3, 2006)
19. Toshiyuki Ohtsuka et al. Visualization of embryonic neural stem cells using Hes promoters in transgenic mice.Mol Cell Neurosci 31 (1) 109-122 (January 2006)
20. M Kucia et al. Cells enriched in markers of neural tissue-committed stem cells reside in the bone marrow and are mobilized into the peripheral blood following stroke.Leukemia 20 (1) 18-28 (January 2006)
21. Zhongjian Zhang et al. Palmitoyl-protein thioesterase-1 deficiency mediates the activation of the unfolded protein response and neuronal apoptosis in INCL.Hum Mol Genet 15 (2) 337-346 (January 15, 2006)
22. Viviane El-Helou et al. Resident nestin+ neural-like cells and fibers are detected in normal and damaged rat myocardium.Hypertension 46 (5) 1219-1225 (November 2005)
23. Natalie D Bull et al. The adult mouse hippocampal progenitor is neurogenic but not a stem cell.J Neurosci 25 (47) 10815-10821 (November 23, 2005)
24. Pasan Fernando et al. Neural stem cell differentiation is dependent upon endogenous caspase 3 activity.FASEB J 19 (12) 1671-1673 (October 2005)
25. Christine Y Brazel et al. Sox2 expression defines a heterogeneous population of neurosphere-forming cells in the adult murine brain.Aging Cell 4 (4) 197-207 (August 2005)
26. M Kucia et al. Bone marrow as a home of heterogenous populations of nonhematopoietic stem cells.Leukemia 19 (7) 1118-1127 (July 2005)

Background References:

1. B A Reynolds et al. Clonal and population analyses demonstrate that an EGF-responsive mammalian embryonic CNS precursor is a stem cell.Dev Biol 175 (1) 1-13 (April 10, 1996)