Keratin 19 Antibody, Clone A53-B/A2

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Mouse Monoclonal Antibody to Human Keratin 19

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  • Vial label for Anti-Human Keratin 19 (Clone A53-B/A2) 100 µg
Vial label for Anti-Human Keratin 19 (Clone A53-B/A2) 100 µg
This antibody recognizes a keratin 19 polypeptide that is expressed in a variety of epithelia, including sebaceous glands, eccrine sweat glands, respiratory epithelium, salivary gland epithelium, gastric epithelium, colonic epithelium, prostatic epithelium and renal epithelium. In the human mammary gland, keratin 19 is expressed in luminal cells of the large ducts, but is expressed only in a subset of luminal epithelial cells in the rest of the mammary tree. Myoepithelial cells do not express this keratin. Thus this can be used as a marker for luminal epithelial cells of mammary gland.
Product Name Description Catalog # Size Price Quantity
Keratin 19 Antibody, Clone A53-B/A2 Mouse monoclonal antibody to human keratin 19 01432 100 µg 153.00 USD      
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Recommended for:
Immunohistochemistry
Intended Use Statement: For Research Use Only. Not for Therapeutic or Diagnostic Use.
Contains:
0.1 mg of antibody at approximately 1 mg/mL in phosphate buffered saline
Immunogen: MCF-7 human breast cancer cells
Clone Name: A53-B/A2
Isotype: IgG2a,k
Product Type: Antibodies
Antibody Type: Primary antibodies
Application: Immunohistochemistry
Area of Interest: Mammary cell research
Cell Type: Mammary epithelial cells
Clonality: Monoclonal
Conjugation: Unconjugated
Host Species: Mouse
Species Reactivity: Human

Procedures and instruction manuals:

Educational resources:

MSDS:

This product has been used in:

  1. J Stingl et al. Characterization of bipotent mammary epithelial progenitor cells in normal adult human breast tissue.Breast Cancer Res Treat 67 (2) 93-109 (May 2001)

Background References:

  1. M Kasper et al. Histological evaluation of three new monoclonal anti-cytokeratin antibodies. 1. Normal tissues.Eur J Cancer Clin Oncol 23 (2) 137-147 (February 1987)
  2. U Karsten et al. Monoclonal anti-cytokeratin antibody from a hybridoma clone generated by electrofusion.Eur J Cancer Clin Oncol 21 (6) 733-740 (June 1985)
  3. J Bartek et al. A subclass of luminal epithelial cells in the human mammary gland, defined by antibodies to cytokeratins.J Cell Sci 75 17-33 (April 1985)
  4. R Moll et al. The catalog of human cytokeratins: patterns of expression in normal epithelia, tumors and cultured cells.Cell 31 (1) 11-24 (November 1982)

Product Name

Description

Catalog #
Keratin 18 Antibody, Clone DC-10 Mouse Monoclonal Antibody to Human Keratin 18 01425
EpiCult®-B Medium Kit (Human) Kit to Culture and Evaluate Human Mammary Epithelial Cells 05601

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