CD44 Antibody, Clone IM7

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Mouse Monoclonal Antibody to CD44

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  • Vial label for Anti-CD44 (Clone IM7) 50 µg
Vial label for Anti-CD44 (Clone IM7) 50 µg
CD44 is a 80-95 kDa type-1 integral transmembrane glycoprotein involved in cell/cell and cell/matrix interactions that regulate cell adhesion, migration, invasion and survival. It is expressed by a wide variety of cells, including leukocytes, epithelial, endothelial and mesenchymal cells. CD44 exerts influence through its interaction with a variety of ligands including hyaluronic acid, fibronectin, collagens, growth factors, cytokines, chemokines and metalloproteinases. The CD44 gene contains at least 21 exons, of which at least 9 of can be variably spliced and glycosylated to produce several dozen CD44 variant isoforms. This marker was demonstrated to label a population of primitive breast tumor precursor cells.
Product Name Description Catalog # Size Price Quantity
CD44 Antibody, Clone IM7 Mouse monoclonal antibody to CD44 01465 50 µg 277.00 USD      
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Recommended for:
Cell Separation
Intended Use Statement: For Research Use Only. Not for Therapeutic or Diagnostic Use.
Contains:
50 µg of antibody in phosphate buffered saline with 0.09% sodium azide
Immunogen: Dexamethone-induced myeloid leukemia M1 cells
Clone Name: IM7
Isotype: IgG2b,k
Product Type: Antibodies
Antibody Type: Primary antibodies
Application: Cell isolation
Area of Interest: Mammary cell research
Cell Type: Mammary epithelial cells
Clonality: Monoclonal
Conjugation: Unconjugated
Host Species: Rat
Species Reactivity: Human, Mouse

Procedures and instruction manuals:

Educational resources:

MSDS:

Background References:

  1. David Naor et al. CD44 in rheumatoid arthritis.Arthritis Res Ther 5 (3) 105-115 (2003)
  2. Ling Lin et al. Perturbation of CD44 function affects chiasmatic routing of retinal axons in brain slice preparations of the mouse retinofugal pathway.Eur J Neurosci 17 (11) 2299-2312 (June 2003)
  3. Joanna Cichy et al. The liberation of CD44.The Journal of cell biology 161 (5) 839-843 (June 9, 2003)
  4. Helmut Ponta et al. CD44: from adhesion molecules to signalling regulators.Nat Rev Mol Cell Biol 4 (1) 33-45 (January 2003)
  5. L J Picker et al. Monoclonal antibodies against the CD44 [In(Lu)-related p80], and Pgp-1 antigens in man recognize the Hermes class of lymphocyte homing receptors.J Immunol 142 (6) 2046-2051 (March 15, 1989)
  6. J Lesley et al. Genetic characterization of a polymorphic murine cell-surface glycoprotein.Immunogenetics 15 (3) 313-320 (March 1982)
  7. I S Trowbridge et al. Biochemical characterization and cellular distribution of a polymorphic, murine cell-surface glycoprotein expressed on lymphoid tissues.Immunogenetics 15 (3) 299-312 (March 1982)

Product Name

Description

Catalog #
CD44 Antibody, Clone IM7, Biotin-Conjugated Rat Monoclonal Antibody to CD44 - Biotin Conjugated 10232
CD44 Antibody, Clone IM7, FITC-Conjugated Rat Monoclonal Antibody to CD44 - FITC Conjugated 10432

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