CD34 Antibody, Clone 8G12, PE-Conjugated

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Mouse Monoclonal Antibody to Human CD34 - PE Conjugated

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  • Vial label for Anti-Human CD34-PE (Clone 8G12) 100 tests
Vial label for Anti-Human CD34-PE (Clone 8G12) 100 tests
CD34 is expressed on hematopoietic stem cells and on progenitor cells of all blood cell lineages. CD34 is also expressed on bone marrow stromal cells and on endothelial cells. CD34 is expressed on ~1-4% of nucleated BM cells and ~0.1-1% of umbilical cord blood cells. CD34+ cells are present in normal peripheral blood at very low frequencies (less than 0.1%), but they can be mobilized from the BM into the blood stream by exposure to cytoreductive therapy or administration of cytokines. CD34 is a highly N- and O-glycosylated type I transmembrane glycoprotein. Monoclonal antibodies against CD34 can be separated into three classes based on their reactivity against carbohydrate or protein epitopes. Class I anti-CD34 monoclonal antibodies recognize epitopes that contain sialic acid residues. Class II antibodies also recognize carbohydrate epitopes, but class II epitopes are not destroyed by desialylation; class III antibodies recognize epitopes on the CD34 polypeptide. Clone 8G12 and 563 are both specific for class III epitopes. Clone 8G12 does not recognize rhesus macaque CD34.
Product Name Description Catalog # Size Price Quantity
CD34 Antibody, Clone 8G12, PE-Conjugated Mouse monoclonal antibody to human CD34 - PE conjugated 10513 100 Tests 778.00 USD      
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Recommended for:
• Cell Separation
• Flow Cytometry
Intended Use Statement: For Research Use Only. Not for Therapeutic or Diagnostic Use.
Contains:
50 µg in 2 mL (25 µg/mL) phosphate buffered saline containing gelatin and 0.1% sodium azide
Clone Name: 8G12
Isotype: IgG1,k
Product Type: Antibodies
Antibody Type: Primary antibodies
Application: Cell isolation, Flow cytometry
Area of Interest: Hematopoietic stem cell research
Cell Type: Hematopoietic stem & progenitor cells
Clonality: Monoclonal
Conjugation: PE
Host Species: Mouse
Species Reactivity: Human

Procedures and instruction manuals:

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Product Name

Description

Catalog #
CD34 Antibody, Clone 8G12, FITC-Conjugated Mouse Monoclonal Antibody to Human CD34 - FITC Conjugated 10413
CD34 Antibody, Clone 8G12, APC-Conjugated Mouse Monoclonal Antibody to Human CD34 - PE Conjugated 10613
CD34 Antibody, Clone 563, PE-Conjugated Mouse Monoclonal Antibody to CD34 - PE Conjugated 10534

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