CD117/c-Kit Antibody, Clone 2B8, APC-Conjugated

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Rat Monoclonal Antibody to Mouse CD117 (c-Kit), APC Conjugated

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  • Vial label for Anti-Mouse CD117 (c-kit)-APC (Clone 2B8) 100 µg
Vial label for Anti-Mouse CD117 (c-kit)-APC (Clone 2B8) 100 µg
CD117 is the receptor for stem cell factor (SCF), c-Kit. In adult mouse bone marrow (BM), CD117 is expressed on hematopoietic stem cells, pluripotent, myelomonocytic and erythroid progenitor cells and B and T lymphocyte precursors. CD117 is also expressed on tissue mast cells, and on subsets of dendritic cells. Anti-CD117 antibody clone 2B8 does not block the epitope that binds SCF. Anti-CD117-APC is recommended for detection of immature Lin-Kit+Sca1+ and Lin-Kit+Sca1- BM subsets by three-colour flow cytometry in combination with FITC-labeled antibodies against lineage-specific antigens (CD3, Catalog #10700; CD11b, Catalog #10705/10706; Gr-1, Catalog #10717/10718; TER119, Catalog #10729) and PE-labeled anti-Sca1 (Catalog #10816). Clone 2B8 was obtained by immunization of Wistar rats with mouse bone marrow mast cells and fusion of immunized rat spleen cells with mouse FOX-NY myeloma cells.
Product Name Description Catalog # Size Price Quantity
CD117/c-Kit Antibody, Clone 2B8, APC-Conjugated Rat monoclonal antibody to mouse CD117 (c-Kit), APC-conjugated 10850 100 µg 637.00 USD      
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Recommended for:
• Cell Separation
• Flow Cytometry
Intended Use Statement: For Research Use Only. Not for Therapeutic or Diagnostic Use.
Contains:
0.1 mg in 0.5 mL (0.2 mg/mL) of an aqueous buffered solution containing 0.09% sodium azide
Immunogen: Mouse bone marrow mast cells
Clone Name: 2B8
Isotype: IgG2b,k
Product Type: Antibodies
Antibody Type: Primary antibodies
Application: Cell isolation, Flow cytometry
Area of Interest: Hematopoietic stem cell research
Cell Type: Hematopoietic stem & progenitor cells
Clonality: Monoclonal
Conjugation: APC
Host Species: Rat
Species Reactivity: Mouse

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