Vancouver, British Columbia, Canada
Description:
STEMCELL Technologies Inc. is a privately-owned biotechnology company that helps power leading-edge life sciences research around the world. Scientists performing stem cell, immunology, cancer, regenerative medicine and cellular therapy research are among those who rely on our cell culture media, cell separation products and ancillary reagents. We have over 400 science-oriented employees, including 100 PhDs/MScs working on the creation of novel products of consistent, unfailing quality, and we stand with our customers around the globe by providing training, one-on-one assistance and technical support. Driven by our love of science and our passion for quality, STEMCELL now delivers over 1500 products to more than 70 countries worldwide.
Currently, we have an opening for a Scientist (Antibody and Hybridoma Technology Platforms) in our Vancouver office. This position is responsible for the development of products related to antibody and hybridoma technology platforms and their associated instrumentation. The successful applicant will help build the antibody business and its ancillary product lines by developing novel antibodies using conventional and recombinant methodologies and identifying new applications for antibodies. The position provides top-level technical support to customers and may function as a Field Applications/Product Specialist to support STEMCELL’s ClonaCell™ reagents and instrumentation product lines. A strong background in antibody development and characterization is required.
Duties:
- Responsible for developing novel antibodies by conventional and recombinant methods, and transition from basic research to tech transfer, launch and technical support
- Design experiments for multiple projects related to hybridoma/recombinant cell line expression and screening with input from Supervisor
- Design and optimize antibody conjugation and purification protocols
- May function as a Field Applications/Product Specialist as needed
- Supervise one or more laboratory staff
- Generate intellectual property, assist in writing patents, evaluate new technologies
- Responsible for project research budget
- Adheres to company Quality program requirements
Qualifications:
- PhD (or equivalent) with 2-4 years direct experience working with antibodies
- Experience with different immunization methodologies (e.g. native or engineered antigen over-expressing cells, cell membranes, DNA immunization, MAP system)
- Well-versed in hybridoma screening methods (e.g. FMAT, ELISA, flow cytometry)
- Experience generating and expressing recombinant antibodies
- Skilled in antibody characterization methods, including affinity measurements (e.g. BIAcore)
- Proven ability in purification and chemical conjugation of antibodies
- Strong knowledge of recombinant DNA technology
- Experience in hybridoma scale-up and large-scale purification an asset
- Works well in a team
- Excellent written and verbal communications skills
- Has supervised laboratory personnel
This is an opportunity to work with highly motivated colleagues in a science-oriented, creative and dynamic environment. We offer a competitive salary, excellent benefits and significant career development opportunities. If you are interested in this challenging and rewarding position, please apply here.